Male sexual dysfunction and liver fibrosis : Are there other secret Players?

Document Type : Original Article


1 Department of Dermatology, Venereology and Andrology, faculty of Medicine, Benha university Egypt.

2 department of dermatology and andrology, benha university, egypt

3 Dermatology and Andrology, Faculty of Medicine, Benha University

4 National Liver Institute, Menoufia University, Egypt.


Background: The effect of advanced liver disease on male sexual health is wellestablished, yet data on sexual disturbances
in liver fibrosis are scant.
Aim: This work aimed to investigate the sexual dysfunctions in male participants with varying stages of fibrosis.
Patients and Methods: A sample of 400 male patients with varying grades of liver fibrosis were subjected to noninvasive
transient elastography (FibroScan) and evaluation of sexual functions using International Index of Erectile Functions (IIEF)
and its short form.
Results: Among studied participants, 57.75% had sexual dysfunction, with a significantly reduced IIEF score accompanying
rising stage of fibrosis (r=0.513, P<0.001). The IIEF score was significantly positively correlated with elevated serum albumin levels (r=0.433, P< 0.001) and hemoglobin levels (r=0.334, P=0.009).
Conclusion: A high percent of patients with liver fibrosis were found to have erectile dysfunction, the severity of which was directly proportional to the stage of fibrosis. Lower serum albumin and hemoglobin levels appear to be attributes.


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